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Gene : |
EPCAM |
Gene ID : |
4072 |
Uniprot ID : |
P16422 |
Alternative Name : |
EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
SPM491 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant full-length human EpCAM protein |
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);