Polyclonal Antibody to HER2

Product code: 11-7565

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Gene : ERBB2
Gene ID : 2064
Uniprot ID : P04626
Alternative Name : HER2, MLN19, NEU, NGL
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant HER2 protein (amino acids 300-550) was used as the immunogen for this antibody.

HER2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12), encoding a type 1 tyrosine kinase growth factor receptor and the role of HER2 in the development of numerous types of human cancer. HER2 is a transmembrane receptor comprising an extracellular domain (ECD), a single transmembrane domain, and an intracellular domain (ICD) with tyrosine-kinase activity.The high-expression and amplification of C-erbB-2 and its protein products (P185) are found in a wide variety of tumors. HER2 is overexpressed in 10% to 35% of gastric and gastroesophageal junction (GEJ) adenocarcinomas.

Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 1-2 µg/ml


Polyclonal Antibody to HER2

Product code: 11-7565
mg

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