|
|
| Gene : |
TRAIP |
| Gene ID : |
10293 |
| Uniprot ID : |
Q9BWF2 |
| Alternative Name : |
TRAIP, RNF206, TRIP |
| Format : |
Sera |
| Amount : |
50 µl |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A synthetic peptide of human TRIP ( amino acids 294-313 ESPAPVEVNLKLRRPSFRDD) was used as immunogen for this antibody |
TRIP (TRAF-interacting protein),also known as TRAIP is a component of receptor-TRAF signaling complexes. Structurally it contains an N-terminal RING finger motif and a putative coiled-coil domain and composed of 469amino acid approximately. TRIP has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation. The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.
WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200
