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Gene : |
USP7 |
Gene ID : |
7874 |
Uniprot ID : |
Q93009 |
Alternative Name : |
USP7, HAUSP |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant USP7 protein (amino acids 932-1100) was used as the immunogen for this antibody. |
USP7 (ubiquitin specific peptidase 7) is a deubiquitinating enzyme that prevents protein degradation by removing poly-ubiquitin chains from its substrates. It regulates stability of a number of human transcription factors and tumor suppressors and plays a critical role in the development of several types of cancer, including prostate and small cell lung cancer.USP7 regulates Pol-eta (DNA polymerase eta) stability through both indirect and direct mechanisms. It regulates the stability of the DNA maintenance methyltransferase. Diseases associated with USP7 include UV-sensitive syndrome.
Western blot analysis: 2-4 µg/ml