|
|
| Gene : |
MLH1 |
| Gene ID : |
4292 |
| Uniprot ID : |
P40692 |
| Alternative Name : |
MLH1, COCA2 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM4D74 |
| Isotype : |
Mouse IgG2b |
| Immunogen Information : |
A partial length recombinant MLH1 protein (amino acids 289-492) was used as the immunogen for this antibody. |
MutL homolog 1 (MLH1) is a member of mismatch repair genes (MMR) that plays a crucial role in correcting replication errors, cell cycle arrest, apoptosis and oxidative stress. MLH1 is a human homolog of the E.coli DNA mismatch repair gene. It mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Diseases associated with MLH1 include colorectal cancer, hereditary nonpolyposis, type 2 and lynch syndrome.
Immunohistochemical analysis: 5-10 µg/ml
