|
|
| Gene : |
KRT40 |
| Gene ID : |
125115 |
| Uniprot ID : |
Q6A162 |
| Alternative Name : |
Cathepsin Z preproprotein, Cathepsin Z, CTSX, Cathepsin
P, Cathepsin X, CTSZ, Cathepsin-Z. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT6G11AT |
| Isotype : |
Mouse IgG2b heavy chain and k light chain. |
| Immunogen Information : |
Anti-human CTSZ mAb,
clone PAT6G11AT, is derived from hybridization of mouse F0 myeloma cells with
spleen cells from BALB/c mice immunized with a recombinant human CTSZ protein 62-303
amino acids purified from E. coli. |
Cathepsin-Z (CTSZ) is a lysosomal cysteine proteinase and member of the peptidase C1 family. CTSZ, which has been also known as cathepsin X and cathepsin P, exhibits carboxy-monopeptidase and carboxy-dipeptidase activities. CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and, similar to other members of this family, takes part in tumorigenesis.
The antibody has been tested by ELISA, Western blot
analysis to assure specificity and reactivity. Since application varies,
however, each investigation should be titrated by the reagent to obtain optimal
results. Recommended starting dilution is 1:1000.
