|
|
Gene : |
ITGAX |
Gene ID : |
3687 |
Uniprot ID : |
P20702 |
Alternative Name : |
ITGAX, CD11C |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
HC1/1 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Human monocytic U937 phorbol ester-treated cells |
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Functional Studies (Order Ab without BSA & Azide);