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Gene : |
GFAP |
Gene ID : |
2670 |
Uniprot ID : |
P14136 |
Alternative Name : |
GFAP |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
ASTRO/789 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant GFAP protein |
This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);