Monoclonal Antibody to TLR10 (Clone: ABM3C85)

Product code: 10-3024

Clonality : Monoclonal
Application : WB
Reactivity : Human

Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

 
Size
Price

Available Pack Size(s)

15,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : TLR10
Gene ID : 81793
Uniprot ID : Q9BXR5
Alternative Name : TLR10, UNQ315/PRO358
Format : Purified
Amount : 100 µg
Clone name : ABM3C85
Isotype : Mouse IgG2a Kappa
Immunogen Information : A partial length recombinant TLR10 protein (amino acids 100-369) was used as the immunogen for this antibody.
TLR10 (Toll-Like Receptor10) is an orphan member of the TLR family and is the only pattern-recognition receptor without known ligand specificity and biological function. This protein plays a role in innate immune responses following viral infection. Influenza virus infection increased TLR10 expression and TLR10 contributed to innate immune sensing of viral infection leading to cytokine induction, including proinflammatory cytokines and interferons. Blocking TLR10 by antagonistic antibodies enhanced proinflammatory cytokine production, including IL-1Beta, specifically after exposure to TLR2 ligands. TLR10 is in a locus that also contains TLR1 and TLR6, two receptors known to function as coreceptors for TLR2. TLR10 is predominantly expressed in tissues rich in immune cells, such as spleen, lymph node, thymus, tonsil, and lung. Expression of TLR10 can be induced in B cells, dendritic cells, eosinophils, and neutrophils, as well as on nonimmune cells, such as trophoblasts.
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml


Monoclonal Antibody to TLR10 (Clone: ABM3C85)

Product code: 10-3024
mg

Can't read the image? click here to refresh.