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Alternative Name : |
Ragulator complex protein LAMTOR2, Endosomal adaptor protein p14, Late endosomal/lysosomal Mp1-interacting protein, Late endosomal/lysosomal adaptor, MAPK, MTOR activator 2, Mitogen-activated protein-binding protein-interacting protein, Roadblock dom |
Amount : |
10 µg |
Source : Escherichia Coli.
LAMTOR2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 148 amino acids (1-125 a.a) and having a molecular mass of 15.9kDa.LAMTOR2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
LAMTOR2 is a member of the GAMAD family. LAMTOR2 is highly conserved with a mouse protein linked with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, which is a component of the mitogen-activated protein kinase pathway. LAMTOR2 gene mutation has been associated with a primary immunodeficiency syndrome in humans, proposing a role for this protein in endosomal biogenesis.