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Alternative Name : |
CIA1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39, CIAO1. |
Amount : |
20 µg |
Source : E.coli.
CIAO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 362 amino acids (1-339a.a) and having a molecular mass of 40kDa. CIAO1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
CIAO1 is a vital component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. CIAO1 protein is required for the maturation of extra mitochondrial Fe/S proteins and seems to specifically modulate the trans-activation activity of WT1. CIAO1 participates in chromosome segregation as a part of the mitotic spindle-associated MMXD complex.