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Alternative Name : |
Dual specificity phosphatase 21, Low molecular weight dual specificity phosphatase 21, LMW-DSP21, BJ-HCC-26 tumor antigen, EC 3.1.3.16, EC 3.1.3.48. |
Amount : |
10 µg |
Source : E.coli.
DUSP21 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 214 amino acids (1-190) and having a molecular mass of 24.1kDa.DUSP21 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
DUSP21 is a member of the protein-tyrosine phosphatase family. DUSPs inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residuesb. DUSP21 is able to dephosphorylate single and diphosphorylated synthetic MAPK peptides, favoring the phosphotyrosine and diphosphorylated forms over phosphothreonine. DUSP21 is only expressed in testis where there are dephosphorylated phosphotyrosine residues in MAPK peptides.