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| Alternative Name : |
Eukaryotic Elongation Factor 2 Kinase, Calcium/Calmodulin-Dependent
Eukaryotic Elongation Factor 2 Kinase, EEF-2 Kinase, EC 2.7.11.20, EEF-2K, Calcium/Calmodulin-Dependent
Eukaryotic Elongation Factor-2 Kinase, Calmodulin-Dependent Protein Kinase III |
| Amount : |
10 µg |
Source : Escherichia Coli.
EEF2K Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 748 amino acids (1-725 a.a) and having a molecular mass of 84.6kDa.
EEF2K is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Eukaryotic elongation factor-2 kinase (EEF2K) is threonine kinase which regulates protein synthesis by means of controlling the rate of peptide chain elongation. Upon activation through a diversity of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a sole site, renders it unable to bind ribosomes and therefore inactive. In turn, the rate of protein synthesis is being reduced.
