|
|
| Gene : |
EGFR |
| Gene ID : |
1956 |
| Uniprot ID : |
P00533 |
| Alternative Name : |
ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR, Proto-oncogene c-ErbB-1 |
| Amount : |
100 µl |
| Immunogen Information : |
Peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y(p)-L-R) derived from Human EGFR |
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Modification: Phospho-Tyr1197
Predicted MW: 175kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
