|
|
Alternative Name : |
Erythropoietin, EP, INN=Epoetin, EPO a, Erythropoietin-alpha,
EPO. |
Amount : |
10 µg |
Source : Escherichia Coli.
EPO a Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 189 amino acids (28-193a.a.) and having a molecular mass of 20.9kDa.EPO a is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
EPO a is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. EPO a is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. EPO a also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.