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Alternative Name : |
PDIA10, TXNDC4, ER protein 44. |
Amount : |
25 µg |
Source : Escherichia Coli.
ERP44 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 415 amino acids (30-406 a.a.) and having a molecular mass of 48 kDa. The ERP44 is fused to a 38 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
ERP44 is an endoplasmic reticulum chaperone that takes part in thiol-dependent retention of the primary secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. ERP44 inhibits the calcium channel activity of ITPR1. ERP44 is involved in the control of oxidative protein folding in the endoplasmic reticulum.