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| Alternative Name : |
TTC11, Tetratricopeptide repeat domain 11, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae). |
| Amount : |
25 µg |
Source : Escherichia Coli.
FIS1 Human Recombinant produced in E.Coli is a single, non-glycosylated,
polypeptide chain containing 142 amino acids (1-122 a.a.) and having a molecular mass of 16.3 kDa. FIS1 protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
FIS1 is part of the mitochondrial complex that promotes mitochondrial fission.
FIS1 induces cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. FIS1 participates in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission.
