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Alternative Name : |
Far upstream element (FUSE) binding protein 1, FUSE-binding protein 1, DNA helicase V, FUBP, FBP, hDH V. |
Amount : |
20 µg |
Source : E.coli.
FUBP1 Human Recombinant produced in E. coli is a single polypeptide chain containing 195 amino acids (279-448) and having a molecular mass of 20.8 kDa.FUBP1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
FUBP1 is a ssDNA binding protein which stimulates expression of c-myc in undifferentiated cells and activates the far upstream element (FUSE) of c-myc. Regulation of FUSE by FUBP happens by single-strand binding of FUBP to the non-coding strand. FUBP1 performs as an ATP-dependent DNA helicase.