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Alternative Name : |
G Antigen 12F, GAGE-12F, G Antigen 12F/G/I. |
Amount : |
10 µg |
Source : Escherichia Coli.
GAGE12F Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids (1-117aa) and having a molecular mass of 15.4kDa.GAGE12F is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GAGE12F
is a member of the GAGE multigene family expressed in a large range of tumors
whereas in normal tissues, his expression is restricted to germ cells. These
genes are organized in clustered repeats, and have a high degree of forecasted sequence
identity, however differ by scattered single nucleotide substitution. Their
sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is
recognized by cytotoxic T-cells.