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|
| Alternative Name : |
G Antigen 2D, Cancer/Testis Antigen 4.8, CT4.8, GAGE-8, GAGE8,
G Antigen 8. |
| Amount : |
10 µg |
Source : Escherichia Coli.
GAGE2D Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (1-116 a.a) and having a molecular mass of 15.2kDa (Molecular size on SDS-PAGE will appear higher).GAGE2D is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GAGE2D is a member of the GAGE family, which organized in clustered
repeats. In addition, they have a high degree of predicted sequence identity, but
differ by scattered single nucleotide substitution. The first GAGE nomenclature was based on
identified mRNA sequences; however the high identity of the GAGE members made it impossible to
separate products of paralogous genes from polymorph products. Moreover GAGE2D
is not expressed in normal tissues, except in testis; however it is expressed
by a large proportion of tumors of various histological origins.
