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| Alternative Name : |
GULP, Engulfment Adaptor PTB Domain Containing 1, PTB
Domain Adapter Protein CED-6, Cell Death Protein 6 Homolog, CED6, GULP, PTB Domain Adaptor Protein
CED-6 Engulfment Adapter Protein,
Protein GULP, CED-6. |
| Amount : |
20 µg |
Source : Escherichia Coli.
GULP1 Human Recombinant produced in E. coli is a single,
non-glycosylated polypeptide chain containing 327 amino acids (1-304a.a) and
having a molecular mass of 36.9kDa.GULP1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
PTB domain-containing engulfment adapter protein 1 (GULP1) is an evolutionarily conserved adaptor protein essential for efficient phagocytosis of apoptotic cells by phagocytes. Furthermore, GULP1 helps modulate cellular glycosphingolipid and cholesterol transport. In addition, GULP1 may have a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are linked with increases in cellular levels of GTP-bound ARF6.
