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| Alternative Name : |
High Mobility Group Nucleosomal Binding Domain 3, TRIP7,
TR-Interacting Protein 7, High Mobility Group Nucleosome-Binding
Domain-Containing Protein 3, Thyroid Hormone Receptor Interacting Protein 7, Thyroid
Receptor-Interacting Protein 7, Thyroid Hor |
| Amount : |
20 µg |
Source : Escherichia Coli.
HMGN3 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 100 amino acids (1-77 a.a) and
having a molecular mass of 10.8 kDa.
HMGN3 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
High Mobility Group Nucleosomal Binding Domain 3 (HMGN3), binds thyroid
hormone receptor beta, however it occurs only in the presence of thyroid
hormone. Thyroid hormone receptors are hormone-dependent transcription factors
which regulate expression of a variety of particular target genes. HMGN3 is considered to reduce the compactness
of the chromatin fiber in nucleosomes, in that way enhancing transcription from
chromatin templates.
