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Alternative Name : |
Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956. |
Amount : |
10 µg |
Source : Escherichia Coli.
Interferon beta 1b Human Recombinant produced in E.Coli is a single, non-glycosylated mutein (variant form) of human Interferon beta-1b polypeptide chain containing 165 amino acids and having a molecular mass of 18510.86 Dalton.The IFN-beta gene was cloned from human fibroblasts and altered to substitute Serine for the Cysteine residue found at position 17. IFN beta-1b is purified by proprietary chromatographic techniques.
Interferon-beta 1b has antiviral, antibacterial and anticancer activities.
It is recommended to reconstitute the lyophilized Interferon beta-1b in sterile 18M?-cm H2O at a concentration of 0.25mg/ml, which can then be further diluted to other aqueous solutions.
The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 32 x 106 IU/mg.