|
|
| Gene : |
SEMA4D |
| Gene ID : |
10507 |
| Uniprot ID : |
Q92854 |
| Alternative Name : |
SEMA4D, C9orf164, CD100, SEMAJ |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
133-1C6 |
| Isotype : |
Mouse IgM, kappa |
| Immunogen Information : |
PHA stimulated human peripheral blood lymphocytes. |
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml);
