|
|
| Gene : |
CD1B |
| Gene ID : |
910 |
| Uniprot ID : |
P29016 |
| Alternative Name : |
CD1B |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
RIV12 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Human peripheral lymphocytes |
The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
ELISA (For coating, order antibody without BSA); Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml);
