|
|
| Gene : |
CD27 |
| Gene ID : |
939 |
| Uniprot ID : |
P26842 |
| Alternative Name : |
CD27, TNFRSF7 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
203.6 |
| Isotype : |
Mouse IgG3, kappa |
| Immunogen Information : |
Sezary cells |
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Flow Cytometry (1-2ug/million cells); ,Immunofluorescence (1-2ug/ml); ,
