|
|
| Gene : |
CDK1 |
| Gene ID : |
983 |
| Uniprot ID : |
P06493 |
| Alternative Name : |
CDK1, CDC2, CDC28A, CDKN1, P34CDC2 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
POH-1; same as cdc2.1 |
| Isotype : |
Mouse IgG2a, kappa |
| Immunogen Information : |
Purified recombinant human p34cdc2 fusion protein |
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Western Blot (1-2ug/ml);Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
