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|
Gene : |
KRT76 |
Gene ID : |
51350 |
Uniprot ID : |
Q01546 |
Alternative Name : |
KRT76, KRT2B, KRT2P |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
KRTH/1076 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant human KRT76 protein |
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);