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Gene : |
Ebi3 |
Gene ID : |
50498 |
Uniprot ID : |
O35228 |
Alternative Name : |
Ebi3, Il27b |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
ABM2C40 |
Isotype : |
Rat IgG2b Kappa |
Immunogen Information : |
A full length recombinant mEBI3 protein was used as the immunogen for this antibody. |
Epstein-Barr Virus?Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.
Western blot analysis: 2-4 µg/ml