|
|
| Gene : |
HSP90B1 |
| Gene ID : |
7184 |
| Uniprot ID : |
P14625 |
| Alternative Name : |
HSP90B1, GRP94, TRA1 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
HSP90B1/1192 |
| Isotype : |
Rat IgG2a, kappa |
| Immunogen Information : |
Recombinant full-length human HSP90B1 protein |
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
