|
|
Gene : |
IGHG1 |
Uniprot ID : |
P01857 |
Alternative Name : |
IGHG1 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
IG217 + IG266 |
Isotype : |
Mouse IgG1, kappa + Mouse IgG2a, kappa |
Immunogen Information : |
Purified human IgG |
This MAb is specific to heavy chain of IgG and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of γ heavy chain (IgG1, IgG2a, IgG2b, IgG3). The most common feature of plasmacytomas, and certain non-Hodgkin?s lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Ab-3 is superb for staining of formalin-fixed tissues.
Flow Cytometry (1ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);