|
|
| Gene : |
NAPSA |
| Gene ID : |
9476 |
| Uniprot ID : |
O96009 |
| Alternative Name : |
NAPSA, NAP1, NAPA |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM4H60 |
| Isotype : |
Mouse IgG1 Kappa |
| Immunogen Information : |
A partial length recombinant Napsin protein (amino acids 150-350) was used as the immunogen for this antibody |
Napsin A, a human aspartic proteinase is found primarily in type II pneumocytes and alveolar macrophages and predominantly expressed in lung and kidney. It is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). It is also useful in evaluating SH (Sclerosing hemangiomas) (23194051). Napsin A acts as an anti-apoptotic protein that promotes resistance to cisplatin by degradation of the tumor suppressor p53, which is regulator of the cell cycle and co-works with cyclin kinase inhibitors as p21 and p27.
Western blot analysis: 2-4 µg/ml; Immunohistochemical analysis: 5-10 µg/ml
Ahmed ahmed
Incidence of Pulmonary Carcinogenic Changes After One Hundred Weeks of Solitary α-quartz Exposure in Albino Wistar Rats (In vivo Study)
Article 4, Volume 44, Issue 2, June 2021, Page 339-348 XMLPDF (909.88 K)
Document Type: Original Article
DOI: 10.21608/EJH.2020.30485.1291
https://ejh.journals.ekb.eg/article_96102.html
