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Gene : |
RBP4 |
Gene ID : |
5950 |
Uniprot ID : |
P02753 |
Alternative Name : |
RBP4, PRO2222 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
RBP/872 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant human retinol binding protein-1 (RBP1) |
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);