|
|
| Gene : |
N |
| Gene ID : |
43740575 |
| Uniprot ID : |
P0DTC9 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM3F2.1C1 |
| Isotype : |
Mouse IgG2b, Kappa |
| Immunogen Information : |
Full length recombinant SARS-CoV-2 nucleocapsid protein was used as the immunogen for this antibody. |
The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.
“This product was developed using BIRAC financial assistance project reference no. BT/COVID0062/02/20”
Recommended dilutions: WB: 0.1-1 µg/ml, ELISA: 1 µg/ml. However, this need to be optimized based on the research applications.
