|
|
| Gene : |
CSTF1 |
| Gene ID : |
1477 |
| Uniprot ID : |
Q05048 |
| Alternative Name : |
Cleavage stimulation factor subunit 1, CF-1 50 kDa
subunit, Cleavage stimulation factor 50 kDa subunit, CSTF 50 kDa subunit,
CstF-50, CSTF1, CstFp50. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT10E11AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mi |
| Isotype : |
Mouse
IgG2b heavy chain and k light chain. |
| Immunogen Information : |
Anti-human CSTF1 mAb,
clone PAT10E11AT, is derived from hybridization of mouse F0 myeloma cells with
spleen cells from BALB/c mice immunized with a recombinant human CSTF1 protein 1-431
amino acids purified from E. coli. |
Cleavage stimulation factor subunit 1 (CSTF1) is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. The CSTF1 gene encodes one of three subunits which merge to produce cleavage stimulation factor (CSTF). Like the mammalian G protein beta subunits, CSTF1 contains transducin-like repeats. CSTF1 is one of the numerous factors necessary for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. CSTF1 is responsible for the interaction of CSTF with other factors to create a stable complex on the pre-mRNA.
The antibody has been tested by ELISA, Western blot
analysis to assure specificity and reactivity. Since application varies,
however, each investigation should be titrated by the reagent to obtain optimal
results. Recommended starting dilution is 1:1000.
