|
|
Gene : |
ORF K4 |
Gene ID : |
4961514 |
Uniprot ID : |
Q98157 |
Alternative Name : |
Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine (C-C motif) ligand 11, SCYA11, MGC22554. |
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
YNRhEOT1. |
Isotype : |
Mouse IgG1. |
Immunogen Information : |
r.Human Eotaxin-1. |
Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophilsby inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligandinclude CCR2, CCR3and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.
Direct ELISA, Western Blot, Immuneprecipitation.