|
|
| Gene : |
GCLM |
| Gene ID : |
2730 |
| Uniprot ID : |
P48507 |
| Alternative Name : |
Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate--cysteine ligase modifier subunit, GCLM, GLCLR. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
P2D12AT. |
| Isotype : |
Mouse IgG1 heavy chain and kappa light chain. |
| Immunogen Information : |
Anti-human GCLM mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GCLM amino acids 1-274 purified from E. coli. |
Glutamate-cysteine ligase (GCLM) is the first rate limiting enzyme of glutathione synthesis. The GCLM enzyme is comprised of 2 subunits, a heavy catalytic subunit and a light regulatory subunit. GCLM deficiency is associated with some forms of hemolytic anemia.
