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|
| Gene : |
HK3 |
| Gene ID : |
3101 |
| Uniprot ID : |
P52790 |
| Alternative Name : |
Hexokinase-3, EC 2.7.1.1, Hexokinase type III, HK III, HXK3, HK3. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
P4F5AT. |
| Isotype : |
Mouse IgG1 heavy chain and ? light chain. |
| Immunogen Information : |
Anti-human Hexokinase-3 mAb is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Hexokinase-3 amino acids 1-923 purified from E. coli. |
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK3 encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. Hexokinase3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase3 may have anabolic functions, providing H6P for glycogen or lipid synthesis.
Hexokinase-3 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
