|
|
| Gene : |
IGF1 |
| Gene ID : |
3479 |
| Uniprot ID : |
P05019 |
| Alternative Name : |
Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF. |
| Format : |
Purified |
| Amount : |
1 mg |
| Clone name : |
NYRhIGF1 |
| Isotype : |
Mouse IgM |
| Immunogen Information : |
r.Human Growth Hormone |
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).
Direct ELISA, Western Blot, Immuneprecipitation.
