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|
Gene : |
IL1RN |
Gene ID : |
3557 |
Uniprot ID : |
P18510 |
Alternative Name : |
IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430. |
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
NYR-hIL1RA. |
Isotype : |
Mouse IgG2b. |
Immunogen Information : |
r.Human IL-1RA. |
Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Direct ELISA, Western Blot, Immuneprecipitation.