|
|
| Gene : |
IL2 |
| Gene ID : |
3558 |
| Uniprot ID : |
P60568 |
| Alternative Name : |
T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2. |
| Format : |
Purified |
| Amount : |
1 mg |
| Clone name : |
YNRhIL2. |
| Isotype : |
Mouse IgG2a. |
| Immunogen Information : |
r.Human IL-2. |
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry, blocking T cell poroliferation.
