|
|
| Gene : |
SSR2 |
| Gene ID : |
6746 |
| Uniprot ID : |
P43308 |
| Alternative Name : |
HSD25, TLAP, TRAP-BETA, TRAPB, Translocon-associated
protein subunit beta, Signal sequence receptor subunit beta, SSR-beta. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT31G6AT |
| Isotype : |
Mouse IgG1 heavy chain and k light chain. |
| Immunogen Information : |
Anti-human SSR2 mAb,
clone PAT31G6AT, is derived from hybridization
of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a
recombinant human SSR2 protein 18-149 amino acids purified from E. coli. |
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum membrane receptor related with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. Diseases correlated with SSR2 include calcaneonavicular coalition, and osteosarcoma, and among its related super-pathways are Viral mRNA Translation and Generic Transcription Pathway.
The antibody has been tested by ELISA, Western blot
analysis to assure specificity and reactivity. Since application varies,
however, each investigation should be titrated by the reagent to obtain optimal
results. Recommended starting dilution is 1:500.
