|
|
Gene : |
TP53 |
Gene ID : |
7157 |
Uniprot ID : |
P04637 |
Format : |
Purified |
Amount : |
0.2 mg |
Clone name : |
PP53SHG. |
Isotype : |
Mouse IgG2a. |
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Western Blot, Immunoprecipitation.