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| Alternative Name : |
Nicotinamide Nucleotide Adenylyltransferase 2, C1orf15, Nicotinate-Nucleotide
Adenylyltransferase 2, NaMN Adenylyltransferase 2, NMN Adenylyltransferase 2, PNAT2,
KIAA0479, Chromosome 1 Open Reading Frame 15 |
| Amount : |
10 µg |
Source : Escherichia Coli.
NMNAT2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 327 amino acids (1-307 a.a) and having a molecular mass of 36.6kDa.NMNAT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Nicotinamide
Nucleotide Adenylyltransferase 2, also known as NMNAT2 is a member of the
nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members
of which catalyze a vital step in NAD (NADP) biosynthetic pathway. Unlike the
other human family member, which is localized to the nucleus, and is
ubiquitously expressed; NMNAT2 is cytoplasmic, and is predominantly
expressed in the brain. Two transcript variants encoding different isoforms
have been found for NMNAT2. Among the diseases associated with NMNAT2 are
tauopathy, and systemic lupus erythematosus.
Specific activity: > 500 pmol/min/ug. One unit will convert 1.0 pmole of beta-NADH per minute to beta-NAD at PH 8.0 at 37°C.
