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Alternative Name : |
Macrophage Migration Inhibitory Factor
(Glycosylation-Inhibiting Factor), Phenylpyruvate Tautomerase, L-Dopachrome
Tautomerase, L-Dopachrome Isomerase,
GLIF, MMIF, GIF, Macrophage
Migration Inhibitory Factor, Glycosylation-Inhibiting Factor, EC 5.3 |
Amount : |
20µg |
Source : Escherichia Coli.
MIF Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 345 amino acids (1-115 a.a) and
having a molecular mass of 39.2kDa.
MIF is fused to a 230 amino
acid GST-tag at N-terminus & purified by proprietary chromatographic
techniques.
The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.