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Alternative Name : |
ECK0697, JW0698, phrB, phr, Deoxyribodipyrimidine
photo-lyase, DNA photolyase, Photoreactivating enzyme, EC=4.1.99.3, b0708.
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Amount : |
10 µg |
Source : Escherichia Coli.
It produced in E.coli is a single, non-glycosylated polypeptide chain containing 495 amino acids (1-472) and
having a molecular mass of 56.1kDa.phrB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Deoxyribodipyrimidine photo-lyase (phrB) is a member of the DNA photolyase class-1 family. phrB takes part in repair of UV radiation-induced
DNA damage. phrB catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between closest bases on the same DNA strand upon exposure to ultraviolet radiation.