|
|
| Gene : |
DRAM1 |
| Gene ID : |
55332 |
| Uniprot ID : |
Q8N682 |
| Alternative Name : |
DRAM1, DRAM |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant DRAM protein (amino acids 1-230) was used as the immunogen for this antibody. |
DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.
Western blot analysis: 4-6 µg/ml
