|
|
Gene : |
TANK |
Gene ID : |
10010 |
Uniprot ID : |
Q92844 |
Alternative Name : |
TANK, ITRAF, TRAF2 |
Format : |
Sera |
Amount : |
50 µl |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A synthetic peptide of human ITRAF (amino acids 346-367 DPSDAPFPSLDSPGKAIRGPQQ) was used as immunogen for this antibody |
TANK/I-TRAF has also been shown to bind to other proteins in the NF-kB signaling pathway, including NEMO.This antibody recognizes TANK/I-TRAF, human TANK/I-TRAF is 425 amino acid protein.These families of proteins are associated with and transduce signals from members of the tumor necrosis factor receptor (TNFR) superfamily. TANK/I-TRAF (TRAF family member associated NF-kB activator/TRAF-interacting protein) that was first defined as a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. The TANK/I-TRAF is thought to inhibit TRAF function by sequestering the TRAFs in the cytoplasm, thereby blocking their recruitment to the TNFR.
WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200