|
|
| Gene : |
RELA |
| Gene ID : |
5970 |
| Uniprot ID : |
Q04206 |
| Alternative Name : |
RELA, NFKB3 |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant p65 protein (amino acids 1-200) was used as the immunogen for this antibody. |
P65 is a subunit of the NF-KappaB, a second messenger, which activates the transcription of a number of genes in multiple tissues. It is a ubiquitously expressed protein that can bind to the kB site alone. In addition, p65 is shown to be the subunit responsible for providing transcriptional activity of the NF-kB (p65-p50) heterodimeric complex. The inhibitory effect of I-KappaB upon NF-KappaB in the cytoplasm is exerted primarily through the interaction with P65. It shows a weak DNA binding site, which could contribute directly to DNA binding in the NF-KappaB complex.
Western blot analysis: 2-4 µg/ml
