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Gene : |
TNFAIP2 |
Gene ID : |
7127 |
Uniprot ID : |
Q03169 |
Alternative Name : |
TNFAIP2 |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant Tnfaip2 protein (amino acids 300-520) was used as the immunogen for this antibody. |
TNFAIP2 (Tumor Necrosis Factor- Alpha Inducible Protein-2) belonging to the SEC6 family was originally identified as a gene transcript induced in endothelial cells following stimulation with TNFAlpha. TNFAIP2 acts as a cell migration-promoting protein and its expression predicts distant metastasis. This protein serves as an independent prognostic indicator for nasopharyngeal carcinoma.TNFAIP2 is induced in a variety of cell types in response a spectrum of pro-inflammatory stimuli, including LPS and IL-1. This protein is normally expressed by follicular dendritic cells, interdigitating dendritic cells, and macrophages but not by lymphoid cells in secondary lymphoid tissues.
Western blot analysis: 4-6 µg/ml